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While several of these strategies have been successful in overcoming BBB limitations, there is also a concern that these new elements could themselves be toxic (Ajdary et al

It has been demonstrated that extracellular GrK influences inflammation (2224) and affects wound healing by impeding epithelialization (21)

Once released into a complex aquatic milieu, an ENM is no longer a static entity but a labile one, subject to a suite of transport phenomena and physicochemical transformations that collectively govern its environmental fate and speciation

10.1136/ard.2008.101279 23 MurrayC

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