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Recombinant Human Arginase I (rhArgI) for Patients with Advanced Hepatocellular Carcinoma (HCC): an Adaptive Design Dose Escalation Trial with Addition of Standard Doxorubicin Treatment

This might have evolved to avoid overlapping functions with class I GRXs and raises questions of whether ROXY9 regulates TGA substrates through redox regulation

In liver transplantation models, blocking mtDNA release (using DNase or Bax/Bak inhibitors to prevent mitochondrial membrane permeabilization) ameliorated injury by avoiding cGAS-STING activation (48)