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Despite advances in antimicrobial therapy and supportive care, sepsis continues to result in high morbidity and mortality, with an estimated 48.9 million cases and 11 million deaths worldwide in 2017, accounting for nearly 20% of all global mortality, disproportionately affecting low- and middle-income countries (Rudd et al., 2020)

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The main SSRIs prescribed for clinical use include fluoxetine, paroxetine, sertraline, and citalopram, among others

While encouraging results are demonstrated in this study, there are still some limitations

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