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Childhood obesity is an early indicator of insulin resistance and a predisposing factor for PCOS, partly due to obesity-mediated reductions in SHBG synthesis, which enhance testosterone bioavailability (88)

In the spinal nerve ligation model, in which anatomic nerve regeneration can be easily observed, nicotine reduced anatomic measures of regeneration as well as expression of regeneration marker growth-associated protein 43 (GAP43)

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Alvarez-Carbonell D, Ye F, Ramanath N, Dobrowolski C, Karn J

For BODIPY 493/503 staining, samples were incubated with 2 M BODIPY 493/503 (1 ml/well) for 30 min at RT