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2025 Apr 20:S0891-5849(25)00235-7

5Amino1MQ is a small molecule peptide that targets nicotinamide Nmethyltransferase (NNMT), an enzyme linked to fat storage and metabolic slowdown

Goeters C, Wenn A, Mertes N, Wempe C, Van Aken H, Stehle P, Bone H: Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients

383 In contrast, anti-inflammatory macrophages (M2) rely more extensively on sustained mitochondrial energy production, which is predominantly fueled by the -oxidation of fatty acids

(A) RT-qPCR analysis of CYP1A1 mRNA expression in HepG2-C3 cells following incubation with 4 M actinomycin D for 1 h and incubation with 10 nM TCDD or 10, 50 or 100 M skatole for 8 h (n = 3)