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Reported effects are mild and transient: Localized irritation or redness at injection site, Mild fatigue or transient headache during initial days, Rare gastrointestinal upset (nausea, stomach discomfort)

For example, mutations in the IVD gene encoding the enzyme for leucine degradation cause isovaleric acidemia, in which the intermediate isovaleric acid accumulates and damages the brain and nervous system (Vockley and Ensenauer, 2006)

Who is most at risk of B12 deficiency

Rotate between two or three sites within the general shoulder region to prevent local tissue irritation