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For example: nicotine - stimulates pleasure to the brain but also causes withdrawal symptoms and the need for more nicotine physical dependence - you smoke because youre in specific situation or with a specific group of people emotional dependence - you smoke to get away from emotional issues, or youre bored

OK a quick Google search of the history of vaping places Herbert and Hon Lik as the founding fathers of e-cigarettes so lets leave it at that

Each brand's cultural footprint reflects its target smoker profile and its original premium cigarette market strategy

[14] [87] In contrast, levoamphetamine may have a greater effect on cataplexy, a symptom more sensitive to the effects of norepinephrine and serotonin

Given nicotines half-life of roughly two hours, nicotine replacement therapies help most with physiological withdrawal, making it possible for smokers to cut down to about 10 cigarettes a day