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Similar alterations have been reproduced in animal models exposed to testosterone esters or nandrolone decanoate, in which mitochondrial dysfunction and caspase-mediated apoptosis occur within Leydig and Sertoli cells (79)

This metabolic dependency positions glutaminolysis as a therapeutic strategy

Vial Size by Protocol Tolerance testing: A 2mg or 5mg vial is the smallest unit cited 1-3 weeks at standard doses Standard 200mcg/day pre-bedtime protocol: 5mg vial 25 days, fits the stability window The most-cited size in vendor sales data 1-2 vials per month Extended cycles: 10mg 5 kit drops cost to $4.40-10/mg Each vial reconstituted only when needed

The activation of these caspases culminates in the cleavage of cellular substrates, inducing tumor cell apoptosis

Lawrence, C