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Cutaneous manifestations include hyperpigmentation, glossitis and hair changes

Together, the results show that our sensitive assay enabled establishment of NAD and glutathione values in a large healthy population cohort, serving as a basis to interpret normal and abnormal values in whole-blood samples

Stromal DHAR was thought to be superfluous, given the fast chemical reduction of dehydroascorbate (DHA) by reduced glutathione (GSH), particularly at alkaline pH (Foyer and Halliwell 1976, 1977)

Note: These studies provide indications of synergistic effects but are not considered definitive proof

This resulted from ectopic storage of fat in the heart, where cardiomyocyte TAG levels were found to have increased twentyfold by 12 weeks of age