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Evidence of the protective effects of phytochemicals, such as SFN, has recently increased due to increased awareness of the induction of phase ll detoxifying enzymes, particularly NQO1 2

Furthermore, transglutaminase 2 can lead to neuronal death during stroke by inducing GSH depletion, thereby promoting ROS accumulation and ferroptosis (65)

Redox dysregulation in disease states 3.1

As elucidated in this review, the GBA and ENS are fundamental drivers of CNS homeostasis and brain plasticity and are therefore fundamental inputs to the development and maintenance of higher-level processes of consciousness, not only for healthy individuals but especially for those on the spectrum or with other neurological challenges

Others have shown that VIP possesses potent anti-inflammatory effects and inhibits eosinophil migration [121]