foxo4-dri senolytic or senomorphic CHK2-USP37 axis stabilizes FOXO4 to
CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway Senolytics: charting a new course or enhancing existing anti tumor therapies? Cellular Oncology Springer Nature Link The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI Results: What to Expect (2026)
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