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Our results thus indicated that AITC treatment led to glutathione depletion which contributed to the higher susceptibility of glutathione mutants, but the molecular mechanism behind this physiological response is likely more complicated

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Therefore, iron has a significant role in enhancing cellular ferroptosis sensitivity (Feng and Stockwell, 2018)

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J Nat Prod 69(3):460463 Prostate cancer statistics| World Cancer Research Fund International [Internet] [cited 2023 Jun 27]

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