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Spautin-1 promotes the degradation of Vps34 complexes, key regulators of autophagy initiation, and has shown promise in preclinical autoimmune models

It is notable that in AS3MT knockout mice, which have markedly impaired arsenic methylation, dramatic cytotoxic urothelial cell changes occur within hours after the administration of sodium arsenite (Arnold et al

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Unreconstituted lyophilised powder remains stable at room temperature for short periods but should be stored at 20C for long-term preservation