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Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-Hydroxy-2-Nonenal

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Nevertheless, a controlled positive charge is advantageous for intranasal and nose-to-brain delivery

Thomas & Capecchi, Cell 51:503-512 (1987)

Future breakthroughs should concentrate on three key areas: 1) the comprehensive integration of metabolomics, single-cell sequencing, and deep learning technologies to accurately analyze the structure-activity relationships of active molecules and their cross-organ regulatory networks