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First, the clinical effectiveness of antipsychotic drugs is directly related to their affinity for DA receptors [55]

230 Phosphodiesterase-5 inhibitors (e.g., sildenafil) increase NO signaling, alleviating PH and RV strains

Carnitine analogs produced by the gut microbiota can colocalize with carnitine in the white matter of the brain and inhibit carnitine-mediated FAO in cell culture models of mouse CNS white matter, affecting the hosts nervous system, which provides a new perspective for understanding the complexity of the gutbrain axis [252]

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Moscovitz et al, 2015