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References 1.Becker RM, Wu G, Galanko JA, Chen W, Maynor AR, Bose CL, Rhoads JM

Importantly, recent studies aimed at blocking the metaorganismal TMAO pathway through multiple approaches have confirmed the inhibition of diet-dependent atherosclerosis in animal models, either by targeting the initial microbial formation of TMA from choline through use of a nonlethal small-molecule inhibitor (19), or by targeting the second step in the pathway, the major host gene responsible for converting microbe-generated TMA into TMAO, flavin monooxygenase 3 (20, 21)

"l-Carnitine and heart disease." Life Sciences

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