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In keeping with the animal and human observational findings, one small placebo-controlled trial involving 24 subjects with asthma noted increased serum selenium concentrations in asthmatics treated with daily oral supplementation of 100 mcg of sodium selenite versus placebo for 14 weeks (133)

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The oral bioavailability of NAC is approximately 6-10%, due to extensive first-pass metabolism, with T max at 1-2 hours after dosing [67]

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