glutathione peroxidase and gsh levels (GSH-Px) activity (a e), superoxide Circulating levels of glutathione peroxidase

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During recent decades, researchers turned to delivery systems based on natural and synthetic polymers and lipids because such liposomes possess valuable qualities, such as the incorporation of hydrophilic and hydrophobic drugs, and membrane penetration ( Application of Exosomes Providing a Novel View for Ferroptosis-Based Cancer Treatment Modified exosomes can be selectively used to deliver drugs to specific cells and present advantages, such as high effectiveness and reduced toxicity

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This redox capability is fundamental to many of its medical applications, including treating methemoglobinemia by converting ferric ions in hemoglobin to ferrous ions

Therefore, in the present study, we demonstrated that serum GPX-3 concentration at diagnosis has the potential to be a novel biomarker that can assess and estimate activity and damage caused by AAV, although it is confined to the time of diagnosis