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At temperatures colder than 25 C, denatured RuBisCO had similar active site density (4.8 10 3 INPs mg 1 ) as native RuBisCO at 8.8 C (4.6 10 3 INPs mg 1 ) (Fig

The authors also reported that mouse embryonic fibroblasts of PAD4 knockout mice showed increased FUS aggregation and sequestration into SGs compared with PAD4 overexpression cells, indicating that citrullination inhibits FUS phase separation 113

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Deficiency leads to nerve damage (neuropathy), which presents as numbness, tingling, or weakness

38 The release of lysosomal enzymes into the cytosol is dependent on the specific lysosomal enzyme cathepsin B