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AOD-9604 is the same fragment with an N-terminal tyrosine modification developed by Metabolic Pharmaceuticals to stabilize the molecule for clinical development

Theoretical Basis for Synergy The potential for synergy between NAD+ and AOD9604 stems from their complementary mechanisms: NAD+ for Cellular Foundation: NAD+ optimizes the fundamental machinery of the cell

While these results seem at odds with the common use of NAC as ROS scavenger, more recent literature shows that NAC also can enhance ROS generation under conditions, where cells express a certain pattern of enzymes that regulate ROS production (53), are co-treated with certain ROS generators (54), or suffer from mitochondrial stress (55)

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Administration Depending on current best practices, treatment may be via injection or other medically approved delivery