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In addition, adipose tissue in the microenvironment is also capable of secreting IGF-1 to support microenvironmental remodeling (75)

Temporary S-glutathionylation of enzymes in the TCA cycle, ETC, or -oxidation pathway protects them from irreversible oxidation when ROS is high but may also hypothetically serve as a mechanism to diminish mitochondrial ROS production by reducing their activity [51]

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By contrast, for linoleic acid, overall peroxidation levels were lower and showed a different pigment-related order of effect: lipofuscin, melanosomes and melanolipofuscin