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14 Most of these patients had been vaping tetrahydrocannabinol (THC), though many used both nicotine-and THC-containing products, and others used products containing nicotine exclusively

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In addition to summarizing the general characteristics of the studies, we demonstrated the distribution of the studies by study designs, risk of bias, risk of cancer, type of exposure, and subgroup findings by harvest plots 7

They typically present as: Brown to dark brown or black patches concentrated on the lower lip and along the vermilion border (the edge where the lip meets the skin)

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