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On the contrary, the metal(II)-bis-glutathionato conjugates retains the structural motifs for recognition by the glutathione disulfide binding site of the enzyme but are able to kinetically exchange the metal with other thiolates, through the mechanism reported in Section 2

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Targeting acute myeloid leukemia with a proapoptotic peptide conjugated to a toll-like receptor 2-mediated cell-penetrating peptide