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As CDC Director Thomas Frieden put it in a JAMA editorial, Tobacco is, quite simply, in a league of its own in terms of the sheer numbers and varieties of ways it kills and maims people. We also continue to learn about the addictive power of nicotine, and the difficulty of breaking an addiction to it

Particularly with oral thrush, the disease can reach the esophagus

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EXCEPTION: Free samples of smokeless tobacco are only allowed in a "qualified adult-only facility" -- where no person younger than 21 is permitted to enter or be present (or a higher minimum-age if your state or locality has a higher age limit.) Do NOT sell in vending machines UNLESS you operate a "qualified adult-only facility" -- where no person younger than 21 is permitted to enter or be present (or a higher minimum-age if your state or locality has a higher age limit.) Some state laws prohibit tobacco product vending machines

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