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Importantly, afucosylation of IgG1-REW did not compromise its long plasma half-life (16.3 days) compared to WT (9.2 days) in human FcRn-expressing mice (Fig

1 The initiation, also called priming, corresponds to the activation of the immediate-early response genes by pro-inflammatory cytokines, such as tumor necrosis factor alpha (TNF ) 2 and interleulin-6 (IL-6) 3 that induces the G0/G1 transition of quiescent hepatocytes

405 The application of nanocarriers is also being explored to deliver these cholinesterase inhibitors through intranasal administration, intravenous injection, and other methods