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The absence of dramatic day-to-day shifts doesn't indicate problems

Although chronic inflammation, leading to neoplastic transformation, is a well-established clinical phenomenon, the link between Hashimotos thyroiditis and thyroid cancer remains controversial (52a, b)

de Lau, W., Peng, W

However, a major pitfall of polymeric scaffolds for localized drug delivery is the necessary surgical intervention to either administer or remove the scaffold when needed, which may lead to further complications such as excessive scarring, and can lengthen the recovery and rehabilitation process

These are thin enough that most people describe the injection as nearly painless