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In terms of lipid metabolism, -tocopherol and ascorbic acid are not effective in inhibiting ferritin oxidation of LDL at lysosomal pH (Ojo and Leake, 2021)

Its core value lies in unifying nanomaterial design with microbial metabolite biology: nanosystems either deliver immunostimulatory metabolites, trigger in situ synthesis, or reshape microbiota to restore metabolite balance, while minimizing systemic side effects