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The European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) has identified ileus as an adverse reaction associated with GLP-1 receptor agonists, making this a recognised rather than merely theoretical risk

Physical examination confirmed marked ipsilateral sensory and motor loss of the upper extremity

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Concurrently, there is a downregulation in the expression of components of voltage-gated potassium channels, which normally regulate neuronal excitability, repolarization, and frequency of action potentials