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10.1016/j.cmet.2012.12.007 102

Mean terminal half-life for valproate monotherapy ranged from 9 to 16 hours following oral dosing regimens of 250 to 1,000 mg

The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: The jnc 7 report

Common adverse effects include gastrointestinal symptoms such as nausea, diarrhea, vomiting, and constipation, which are typically mild to moderate and often diminish over time