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Cerebral ischemia Cerebral ischemic occurs when there is insufficient blood flow to the brain area, leading to potentially severe damage

Regular monitoring may be appropriate for patients with chronic conditions, ensuring stability and detecting any disease progression

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As shown in Table 1 and Figure 6, in the pursuit of structurally diverse NNMT inhibitors, researchers have identified certain macrocyclic peptides that bind to NNMT, displaying potent inhibition with Half-maximal inhibitory concentration (IC 50 ) values as low as 229 nM (Van Haren et al., 2021)