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Single-cell RNA sequencing reveals the adverse role of cDC3s in the response of ulcerative colitis patients to anti-TNF- therapy

However, the associated costs in design complexity and manufacturing sensitivity position it as a specialized, high-performance tool, to be prioritized when precision-driven translational mandates surpass operational simplicity or cost-efficiency considerations

In the absence of enough iron in cells, an iron starvation response begins, increasing iron availability by increasing TFCR1 and decreasing the levels of FTH and ferroportin (FPN) (34)