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Observations in research suggest that significant changes in skin density, texture, and scar appearance can take 8-12 weeks or longer, consistent with the natural skin remodeling cycle

2024;68: e230197 Assessment of thiol-disulfide and glutathione homeostasis after levothyroxine replacement in individuals with autoimmune or nonautoimmune hypothyroidism DOI: 10.20945/2359-4292-2023-0197 ABSTRACT Objective Thyroid hormones are known to affect the biosynthesis and degradation of antioxidant compounds, suggesting a possible link between hypothyroidism and oxidative stress

This stage of research is crucial for understanding the efficacy and safety of these inhibitors before they can be considered for clinical use

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