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It is due to recessive pathogenic variants that cause complete loss of function of ABCA12,27 with slightly less severe phenotypes in patients with 2 different heterozygous pathogenic variants.28 - Self-improving collodion baby: this is a clinical variant in which the collodion membrane progresses, regardless of its severity, to a mild ARCI phenotype

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51: North America E-Liquid Market Value (US$ Mn), By Flavor 2019-2027 FIG

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However, the difference was not statistically significant (p=0.087)