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The intensity threshold for fragmentation was set to 50,000 for orbitrap and included charge states from 2 + to 7 +

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We measured GSH synthesis rate using an infusion of [ 2 H 2 ]-glycine as isotopic tracer and collection of blood samples for liquid chromatography mass spectrometric analysis

Similar to the interactions of mammalian TrxR with several quinones [35], inhibitory compounds may function as both substrates and inhibitors (i.e., subversive substrates) of TGR