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TrxR works together with thioredoxin (Trx) and reduced coenzyme II (NADPH) to form an antioxidant system [122,123]

Experimental models have examined its influence on vascular endothelial growth factor receptor-2 (VEGFR2) signaling, including activation of downstream VEGFR2AkteNOS pathways associated with endothelial cell proliferation and vascular signaling processes

the isocitrate dehydrogenase (IDH), which converts isocitrate to -ketoglutarate