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Tirzepatide: The Dual Incretin Receptor Agonist Tirzepatide has revolutionized metabolic therapy as the first dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA

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Methods Animal experiment Seven-week-old specific pathogen-free (SPF) grade male BKS-db mice and seven-week-old male db-m mice were purchased from GemPharmatech Co., Ltd

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Aspulvinone O, a natural inhibitor of GOT1 suppresses pancreatic ductal adenocarcinoma cells growth by interfering glutamine metabolism