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Emerging Roles of Energy Metabolism in Ferroptosis Regulation of Tumor Cells

In recent years, research has primarily focused on TET-mediated active demethylation

M.BarnesA

J.BirdD.BurlaB.DassaE.ForestierC.GeislerM.et al

The imported cystine can then be converted to cysteine for the biosynthesis of glutathione and the maintenance of cellular redox homeostasis ( Since the net movement of amino acids into cells can only be mediated by uniporters and symporters ( SLC38A1 ) and SNAT2 ( SLC38A2 ) are uniporters ( SLC38A3 ) ( 0,+ (ATB 0,+ ), a symporter encoded by the SLC6A14 gene, can transport all neutral (including glutamine) and basic amino acids