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Type 1 diabetes mellitus (T1DM), also known as insulin-dependent diabetes, is characterized by the autoimmune destruction of pancreatic beta cells, leading to a complete deficiency of insulin and resulting in chronic hyperglycemia (see Figure 1 )

They observed an upregulation of GGT2 in the KRAS transfected cells and confirmed its role in resistance to hydrogen peroxide treatment

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At the same time, two oral drugs, Deferiprone (DFP) and Deferasirox (DFX) , have been developed to address the short half-life of DFO , but side effects such as granulocyte deficiency (Lecornec et al., 2022)and renal failure (Kattamis, 2019)are still present during treatment

Bloating and gas still occur but at seemingly lower rates