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It makes a fluid called bile that helps your body digest food

Symptom-based stratification of patients with primary Sjgrens syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials

And it was found for the first time that ISL could inhibit Annexin A2 expression both in vivo and in vitro , block the sphingosine kinases/sphingosine-1-phosphate/IL-17 signaling pathway and regulate the expression of -SMA by inhibiting the phosphorylation of STAT3 at the downstream signal to finally reverse HSCs activation and hepatic fibrosis (Liu et al., 2023)