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Inflammasome Regulation: Therapeutic Potential for Inflammatory Bowel Disease

Odevixibat, a small molecule that inhibits ileal resorption of BAs belonging to the class of ileal BAs transporter (IBAT) inhibitors, was the first drug approved for the treatment of PFIC patients 6 months old due to its efficacy on both pruritus and reduction of serum BAs as well as its good tolerability in 2021 [16]

Brood count Worm populations (F1) were age-synchronized by placing 10 adult, egg-laying worms (P0) on plates for a 4-h period

The lightweight, fast-absorbing formula is specifically designed for microneedling applications, allowing active ingredients to penetrate effectively through treatment-created micro-channels

Unlike single-compound treatments such as pure GSH, the multifaceted composition of APE may offer broader biological benefits, including modulation of redox-sensitive signalling pathways and enhancement of endogenous antioxidant defence