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Description

Because the skin is the protective barrier to the environment, it can receive direct oxidative damage in the epidermis

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Therefore, even in the presence of higher PGC-1 gene expression as a result of mTOR hyperactivity during early AMD stages, a reduction in PGC-1 activity in later stages could ultimately affect mitochondrial turnover and biogenesis causing increased ROS production and cell death

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Biological Activity Glutathione synthase/GSS protein catalyzes the ATP-dependent synthesis of glutathione from gamma-glutamylcysteine and glycine

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These tissue sections were deparaffinized in graded xylene, rehydrated in graded alcohol solutions, and then incubated in antigen retrieval buffer (Roche, Basel, Switzerland) at 37 C for 30 min

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