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DHODH is a flavin-dependent protein, present in the inner mitochondrial membrane, that converts DHO to orotate, reducing ubiquitin to pantothenol and producing lipophilic antioxidants, which inhibits LPO accumulation and ferroptosis (46)

6.10.3 Matrix Deposition Fibroblasts are essential for effective repair, depositing and remodelling ECM and mediating wound contraction

Methods The guideline panel used the adapted ADAPTE methodology

Plants 8(2):43

Other Ingredients:Water, Aloe (Aloe vera barbadensis) (leaf) juice, propanediol (all natural, petroleum-free), MSM (methylsulfonylmethane), cetyl alcohol, urea, octyl palmitate, triethanolamine, stearic acid (vegetable source), panthenol, PEG-8 stearate, glycerin, polysorbate 65, coconut (Cocos nuciferas), gardenia (Gardenia tahitensis) (flower) extract, sodium hyaluronate, natural vitamin E (d-tocopheryl), TEA-carbomer, orange (Citrus aurantium dulcis)(peel) oil, diazolidinyl urea, iodopropynyl butylcarbamate, grapefruit (Citrus grandis) (peel) oil,grapefruit (Citrusgrandis) (peel) extract