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At astrocyte stage, there is a negative regulation of terms reflecting a reduction in the recruitment of protein complexes to chromatin (regulation of protein localization to chromatin), recognition of acetylated histones typically associated with open chromatin and active transcription (lysine acetylated histone binding, acetylation-dependent protein binding), and fine-tuning transcriptional repression (SUMO ligase complex), potentially leading to impaired gene activation and aberrant chromatin states

Anant S, Davidson NO

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612 The STABLE method utilizes emulsions and streptavidin fused polypeptides to link the biotinylated template DNA to the expressed protein