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Also, there is no alternative method whereby homocysteine can be remethylated to methionine since betaine-homocysteine methyltransferase is absent in the brain

In-situ Regeneration (In-vessel Regeneration) As discussed previously, this method involves the resin remaining entirely within the mixed bed vessel throughout the entire processincluding backwashing, regeneration, rinsing, and mixing

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It is a small, naturally occurring peptide that binds to copper ions