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Frozen storage ( 20 C): Preferred for long-term storage, with containers sealed to prevent moisture uptake and degradation

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GHK-Cu activates lysyl oxidase and prolyl hydroxylase enzymes, important for cross-linking collagen fibers and maintaining skin structure (Pickart, Biochemical Pharmacology, 2008)

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In contrast, cell death was negligible when normal chondrocytes were co-cultured with NPs (Fig

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