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: impairment of DNA methylation maintenance is the main cause of global demethylation in naive embryonic stem cells

(1996) who also did not observe any statistically significant change in rodents during aging to 30 months

Based on preliminary experiments, mice were randomized into three groups: control (vehicle only), low-dose resveratrol (50 mg/kg/day), and high-dose resveratrol (100 mg/kg/day)