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Significantly downregulated metabolites included glutamine, isoleucine, deamido-NAD + , and MG (PGF2/0:0/0:0), while upregulated metabolites included acylcarnitines, succinyladenosine, and leukotriene B4

Protein Cell 15 , 8397 (2024)

however, the partial inhibition of the electron transport chain by KG reportedly extends the lifespan of C

Proteomic analysis of single mammalian cells enabled by microfluidic nanodroplet sample preparation and ultrasensitive NanoLC-MS

Recent studies have demonstrated that the downregulation of let-7 can upregulate the expression of IGF1/IGF1R by mediating the IGF1 signaling cascade to promote the differentiation of spermatogonia into primary spermatocytes 15