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The regulation of Ca signaling in astrocytes is primarily mediated by inositol trisphosphate receptors (IP3Rs), which have been studied for their potential roles in brain damage and neuronal death in mouse models 100

3 Use of an antiandrogen without a COCP necessitates continued use of an alternative form of effective contraception due to the teratogenic potential for feminization of a male fetus

However, only very small amounts are needed and, although theres limited evidence to suggest what effects high doses may have, you should avoid taking too much as this may be harmful

Your provider may recommend regular lab tests (e.g., liver function, kidney function) to monitor safety and effectiveness

[DOI] [PMC free article] [PubMed] [Google Scholar] Sjogren K, Bohlooly YM, Olsson B, Coschigano K, Tornell J, Mohan S, Isaksson OG, Baumann G, Kopchick J, Ohlsson C