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Significant increases in genotoxicity or expression of proteins involved in mutagenesis were found following acute exposure to nicotine e-cigarette in 6 studies 28,34-37,42 , following short-to-medium term exposure in 1 study 33 , and following non-nicotine e-cigarette exposure in 1 study 25

Older nicotine products like chewing tobacco and snuff are just as bad as smoking

However, the age requirement to buy cannabis or weed from a licensed vendor varies from 18 to 21 years old

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How cigarette smoke skews immune responses to promote infection, lung disease and cancer