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Name: walter klower Wolters Kluwer Wolters Kluwer Health Logo Kluwer
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PMID: 16275827

Thus, these trials have not been addressed in the present manuscript

Use of melatonin in combined treatment for inflammatory bowel diseases

In a rat model of adjuvant-induced arthritis, the combination of metformin (200 mg/kg/day) and omega-3 (300 mg/kg/day) showed efficacy comparable to methotrexate (2 mg/kg/week) in ameliorating disease activity, with significant reductions in arthritic scores, paw swelling, and serum TNF- and IL-1 after 4 weeks (252)